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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CMIP
All Species:
19.7
Human Site:
S222
Identified Species:
48.15
UniProt:
Q8IY22
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY22
NP_085132.1
739
82975
S222
H
C
R
E
R
P
R
S
M
V
V
I
E
V
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109725
1040
115469
S523
H
C
R
E
R
P
R
S
M
V
V
I
E
V
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D486
739
82826
S222
H
C
R
E
R
P
R
S
M
V
V
I
E
V
F
Rat
Rattus norvegicus
Q5MJ12
479
51833
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507966
653
73509
L172
L
F
T
Q
E
Y
I
L
A
L
N
E
L
N
A
Chicken
Gallus gallus
XP_423491
772
86619
S255
H
C
R
E
R
P
R
S
M
V
V
I
E
V
F
Frog
Xenopus laevis
A1L3F5
739
83452
S222
H
C
R
E
R
P
R
S
M
V
V
I
E
V
F
Zebra Danio
Brachydanio rerio
XP_690387
687
76914
P189
N
M
D
F
G
K
C
P
R
L
R
L
F
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397222
587
65892
V106
K
H
L
E
D
S
V
V
E
S
P
I
E
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147302
582
63441
T100
L
V
N
S
N
R
L
T
E
A
S
L
Q
V
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
67.8
N.A.
N.A.
98.7
21.1
N.A.
81.7
91.1
92.2
80.2
N.A.
N.A.
35.9
N.A.
N.A.
Protein Similarity:
100
N.A.
69.4
N.A.
N.A.
99.1
33.4
N.A.
84.7
93.2
95.9
84.5
N.A.
N.A.
52
N.A.
N.A.
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
0
N.A.
0
100
100
0
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
0
N.A.
13.3
100
100
20
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
22
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
37.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
10
% A
% Cys:
0
50
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
60
10
0
0
0
20
0
0
10
60
0
0
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
60
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
50
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
60
0
0
0
% I
% Lys:
10
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
20
0
10
0
0
0
10
10
0
20
0
20
10
0
0
% L
% Met:
0
10
0
0
0
0
0
0
50
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
10
0
0
0
0
0
10
0
0
10
10
% N
% Pro:
0
0
0
0
0
50
0
10
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% Q
% Arg:
0
0
50
0
50
10
50
0
10
0
10
0
0
0
0
% R
% Ser:
0
0
0
10
0
10
0
50
0
10
10
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% T
% Val:
0
10
0
0
0
0
10
10
0
50
50
0
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _